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pentobarbital will reduce the level or outcome of piroxicam by influencing hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Unidentified.pentobarbital will reduce the extent or impact of artemether/lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration with potent CYP3A4